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21c Museum Hotel Louisville

Photo gallery for 21c Museum Hotel Louisville

Front of property
A room with a geometric-patterned ceiling, a bed with a patterned bedspread, and a nightstand with a lamp.
Breakfast, lunch, dinner and brunch served
Room (Asleep in the Cyclone)
Fountain

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Spa
  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Gym
The current price is NZ$324
includes taxes & fees
27 July - 28 July

Explore the area

View map
700 W Main Street, Louisville, KY, 40202
  • Place, 21c Museum Hotel
    ‪1 min walk‬
  • Place, Muhammad Ali Center
    ‪3 min walk‬
  • Place, Louisville Slugger Museum
    ‪3 min walk‬
  • Airport, Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

Room options

View all photos for Deluxe Double Room, 2 Double Beds

A hotel room with two beds, a headboard with a framed artwork of birds, a bedside table with a lamp, and a small bookshelf.

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(32 reviews)
  • 31 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Luxury Double Room, 2 Double Beds

A hotel room with two beds, a desk, a chair, a lamp, and a large window with a view.

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 40 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(73 reviews)
  • 33 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

9.2 out of 10
Wonderful
(35 reviews)
  • City view
  • 42 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, Corner

Suite, Corner

Suite, Corner

  • City view
  • 61 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room (Asleep in the Cyclone)

A room with a geometric-patterned ceiling, a bed with a patterned bedspread, and a nightstand with a lamp.

Room (Asleep in the Cyclone)

  • 46 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite (Atrium)

A hotel room with a bed, desk, chair, dresser, and a sofa.

Suite (Atrium)

  • 54 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room, Balcony

Room, Balcony

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • City view
  • 29 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Deluxe Double Room, Accessible

Designer toiletries, hair dryer, bathrobes, towels

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 42 sq m
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(2 reviews)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Apartment, 1 Double Bed (Rooftop)

A modern interior with a dining area, a patterned bench, and a large window with a city view.

Apartment, 1 Double Bed (Rooftop)

10.0 out of 10
Exceptional
(1 review)
  • City view
  • Sleeps 4
  • 1 Double Bed
  • Free Wi-Fi

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About the area

Louisville

A luxury stay in the heart of Louisville awaits you at 21c Museum Hotel Louisville. Within steps you'll find Louisville Slugger Museum and KFC Yum Center within a 10-minute stroll. Highlights at this boutique hotel include in-room free WiFi, free high-speed Internet and LCD TVs. .A day of pampering at 21c Spa can include deep-tissue massages and hot stone massages along with access to the sauna and steam room. The fine-dining restaurant, Proof on Main, is open for breakfast, brunch, lunch and dinner. The hotel's own lounge bar is a nice place to enjoy a drink. 5000 square feet (465 square metres) of event facilities include meeting rooms and conference space, and other business amenities include a 24-hour business centre and limo/town car service. Plus you'll find free Wi-Fi in public areas, a 24-hour gym and coffee/tea in a common area. Full breakfast is available on weekdays between 7:00 AM and 10:00 AM and on weekends between 8:00 AM and 1:00 PM. Bring your pet along and take advantage of this property's pet-friendly amenities, such as food and water bowls. There's also the convenience of valet parking. .Attractions within a 10-minute walk of this 4.5-property class Downtown Louisville hotel include Fourth Street Live! and Whiskey Row.

What's nearby

  • 21c Museum Hotel - 1 min walk - 0.1 km
  • Muhammad Ali Center - 3 min walk - 0.3 km
  • Louisville Slugger Museum - 3 min walk - 0.3 km
  • Kentucky Bourbon Trail Visitor Center - 5 min walk - 0.4 km
  • KFC Yum Center - 8 min walk - 0.7 km

Getting around

  • Louisville International Airport (SDF) - 10 min drive

Restaurants

  • ‪Thelma's Deli - ‬7 min walk
  • ‪Heine Brothers' Coffee - ‬3 min walk
  • ‪Swizzle - ‬7 min walk
  • ‪Vincenzo's Italian Restaurant - ‬5 min walk
  • ‪Sunergos Coffee and Espresso Bar - ‬6 min walk

About this property

21c Museum Hotel Louisville

21c Museum Hotel Louisville offers its guests a full-service spa and a 24-hour fitness centre. There's a restaurant on site. You can enjoy a drink at the bar/lounge. A computer station is on site, and both WiFi and wired Internet are free in public spaces.

A 24-hour business centre, meeting rooms, and limo/town car service are available. Event space at this hotel measures 5000 square feet (465 square metres) and includes conference space. Spa services, multilingual staff, and gift shops/newsstands are also featured at the luxury 21c Museum Hotel Louisville. Parking is available for a fee.

This 4.5-star Louisville hotel is smoke free.

  • 1 building
  • 91 guestrooms or units
  • 4 levels
  • Conference rooms
  • 5000 sq ft of conference space
  • 465 sq. m of conference space
  • Built in 2006
  • Charging station for electric cars
  • Business centre (24 hours)
  • Conference space
  • Breakfast available (surcharge)
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Staff members are multilingual
  • Storage area for luggage
  • Front desk safe
  • Car service
  • Tour and ticket information
  • Concierge
  • Gift shop
  • ATM
  • Bellhop
  • Lift
  • No smoking on site
  • Bar or lounge
  • Dining venue
21c Museum Hotel Louisville offers 91 accommodations with minibars and laptop-compatible safes. Beds feature down duvets and premium bedding. 50-inch LCD televisions come with premium cable channels. Bathrooms include bathrobes, designer toiletries, complimentary toiletries and hairdryers.

This Louisville hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Additionally, rooms include espresso makers and complimentary bottles of water. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided on a daily basis.

21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.

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includes taxes & fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Limited on-site valet parking
  • Wheelchair-accessible parking available

Food and drink

  • Full breakfast available for a fee 7:00 AM to 10:00 AM on weekdays and 8:00 AM to 1:00 PM on weekends; USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room cot
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance

Business services

  • 24-hour business centre
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • Deep-tissue massages
  • Hot stone massages
  • In-room massages
  • Prenatal massages
  • Sauna
  • Spa open daily
  • Sports massages
  • Steam room
  • Swedish massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Lift
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Built in 2006
  • Comprehensive food waste policy
  • Double-glazed windows
  • Eco-friendly cleaning products used
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Non-plastic coffee stirrers available
  • Non-plastic drinking straws available
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed
  • Some LED lighting used
  • Vegan dining options

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free cot
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Designer toiletries
  • Dressing gowns
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • IPod dock

Food and drink

  • Champagne service
  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; check-in end time: midnight
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 40.00 per accommodation, per stay
  • Weight limit: 50 lb per pet
  • Food and water bowls are available
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are available for USD 30.0 per night.
  • Free cots (infant beds)!

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5.00 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
Charges for extra guests may apply and vary according to property policy.
A credit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guest room reservation. This property accepts Visa, Mastercard, American Express and Discover. Cash is not accepted. 
    For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit and window guards in all accommodation. This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels) guidelines.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
21c Museum Hotel Louisville - MGallery Louisville
Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
21c Museum Louisville Mgallery
21c Museum Louisville
21c Museum Hotel Louisville Hotel
21c Museum Hotel Louisville MGallery
21c Museum Hotel Louisville Louisville
21c Museum Hotel Louisville Hotel Louisville

Frequently asked questions

What is the cancellation policy at 21c Museum Hotel Louisville?

21c Museum Hotel Louisville offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of 1 Jul 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on 27 Jul 2026 start from NZ$324, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21c Museum Hotel Louisville?

Yep, 21c Museum Hotel Louisville has valet parking with in/out privileges for USD 32 per night.

Is there a spa on site at 21c Museum Hotel Louisville?

Yep, 21c Spa is available for guests. It has a steam room and a sauna. You'll enjoy services like sports massages.

What makes 21c Museum Hotel Louisville a romantic place to stay?

A champagne service and a lounge bar, as well as premium bedding and massage services available in the guestrooms, help set the scene for a romantic weekend at 21c Museum Hotel Louisville.

Is 21c Museum Hotel Louisville family-friendly?

You bet! With amenities such as laundry facilities, as well as free infant beds in the guestrooms, it's no surprise that 21c Museum Hotel Louisville is a hit with families.

Does 21c Museum Hotel Louisville serve breakfast?

You bet, full brekkie is on offer weekdays between 7:00 AM and 10:00 AM and on weekends from 8:00 AM to 1:00 PM.

Is there a free airport shuttle available at 21c Museum Hotel Louisville?

No, 21c Museum Hotel Louisville does not offer an airport shuttle service.

Is there a bar or restaurant at 21c Museum Hotel Louisville?

Yep, they've got a lounge bar and an onsite restaurant that serves breakfast, brunch, lunch and dinner.

What time are check-in & check-out at 21c Museum Hotel Louisville?

Check-in begins at 4 PM. Check-out time is 11 AM.

Are pets allowed at 21c Museum Hotel Louisville?

Furry friends are welcome at 21c Museum Hotel Louisville, with food and water bowls on offer. Just so you know, there's a weight limit of up to 23 kg per pet.

21c Museum Hotel Louisville Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 777 out of 1001 reviews
Rating 8 - Good. 126 out of 1001 reviews
Rating 6 - Okay. 60 out of 1001 reviews
Rating 4 - Poor. 21 out of 1001 reviews
Rating 2 - Terrible. 17 out of 1001 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Kristin Woxland

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely hotel. Would stay there again.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Meredith

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Brent

Liked: Cleanliness, amenities, property conditions & facilities
Nice room and close to all the distilleries. Great restaurant on site as well!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

KARI

Liked: Cleanliness, staff & service, property conditions & facilities
The stay was amzn!!!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Salvatore

Liked: Cleanliness, amenities, property conditions & facilities
Clean hotel…very cool vibe!!!
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Dean

Liked: Cleanliness, staff & service, amenities
Great room and amenities.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Amanada

Liked: Cleanliness, amenities, property conditions & facilities
Large spacious room and super comfortable bed Fascinating art and super bar and restaurant too Great service from all staff
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Elizabeth

Liked: Cleanliness, staff & service, amenities
The staff was super friendly
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff and a wonderful lobby experience. Room was spacious and clean. Restaurant and bar were both very good.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Madeline

Liked: Cleanliness, amenities, property conditions & facilities
Location and the staff was fabulous.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

MARC

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The rooms and staff were great and the penguins were alive.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Casey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really cool place, great location. Very glad we chose this one. Would definitely recommend.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Rachel

Liked: Cleanliness, amenities, property conditions & facilities
Great room, super kind staff
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Joshua

Liked: Cleanliness, property conditions & facilities
This was an amazing hotel! Loved all the art and the bed was super comfortable. Hope to return one day!
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Karen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Fun hotel, lots of interesting art, very comfortable, excellent staff
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

pamela

Liked: Cleanliness, property conditions & facilities
Lovely comfortable place to stay !
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Michael

Interesting Ambiente, very knowledgeable and friendly staff, great bar and good food in the restaurant with special choices.
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Anatole

Liked: Cleanliness, amenities, property conditions & facilities
Excellent place.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Douglas

Liked: Cleanliness, staff & service, amenities
clean rooms, outgoing and friendly staff. The vibe is warm and fun, love the penguins
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Thea

Liked: Cleanliness, amenities, property conditions & facilities
Great atmosphere, love the art that surrounds you at every turn
Stayed 3 nights in Jan 2026
Verified

10/10 Excellent

Jeannie

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, art work is beautiful, friendly staff .
Stayed 1 night in Jan 2026
Verified

8/10 Good

Stacy

Liked: Cleanliness, amenities, property conditions & facilities
Great location for Whiskey Row in Downtown Louisville. Hotel was clean, artsy and has a great restaurant on site.
Stayed 2 nights in Jan 2026
Verified

8/10 Good

Donna M

Liked: Cleanliness, staff & service, property conditions & facilities
Prices are exceptionally high (probably the same as everywhere) for what you get in the restaurants.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

JEFF

Liked: Cleanliness, amenities, property conditions & facilities
Fantastic, caring staff in an artsy and fun environment.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Lorie

Liked: Cleanliness, staff & service, amenities
All the staff were great! The rooms were clean the coffee was great. I would stay here again.
Stayed 2 nights in Jan 2026