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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Hotel in Cape Girardeau with full-service spa and indoor pool

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Free breakfast
Exterior
Indoor pool, open 8 AM to 11 PM, pool loungers
Suite, 1 Bedroom (Feature)

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Parking included
  • Free Wi-Fi
  • Air-conditioning
The current price is NZ$185
includes taxes & fees
1 Mar - 2 Mar

Explore the area

View map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Saint Francis Medical Center
    ‪6 min walk‬
  • Place, Southeast Missouri State University
    ‪6 min drive‬
  • Place, Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.4 out of 10
Exceptional
(6 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(55 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

About the area

Cape Girardeau

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG you'll be within a 15-minute walk of Saint Francis Medical Center and 4 km (2.5 mi) from Saint Francis Healthcare System. Highlights at this hotel include a full-service spa, an indoor swimming pool and free breakfast. .Enjoy the gym and pool loungers. 118 square feet (11 square metres) of event facilities include a meeting room and conference space, and other business amenities include a business centre. Other amenities include free Wi-Fi in public areas and laundry facilities. There's also the convenience of free self parking. .Attractions within a 10-minute drive of this Cape Girardeau hotel include Shawnee National Forest and Mississippi River.

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.6 km
  • Southeast Missouri State University - 6 min drive - 6.3 km
  • Isle Casino Cape Girardeau - 8 min drive - 9.1 km
  • Show Me Center - 9 min drive - 9.1 km
  • Giant City State Park - 61 min drive - 77.9 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪White Castle - ‬10 min walk
  • ‪Wings Etc. - ‬9 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with full-service spa and indoor pool
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness centre. Public spaces have free WiFi and wired Internet. A business centre and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square metres) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq. m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with a safe and coffee/tea makers. This accommodation offers separate sitting areas. Pillowtop beds feature down duvets and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hairdryers.

Guests can surf the web using complimentary wired and wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Housekeeping is provided on a daily basis.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
  • Pool
  • Spa pool
  • Breakfast included
  • Pet-friendly
4.8 out of 5, Exceptional, 1,006 reviews
The price is NZ$187
includes taxes & fees
19 Feb - 20 Feb
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business centre
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cots (infant beds) are not available.

Payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in all accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG) guidelines.

We should mention

  • Pool access available from 8 AM to 11 PM
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

What is the cancellation policy at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of 15 Feb 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on 1 Mar 2026 start from NZ$184.91, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a free self car park.

Is there a spa on site at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, there is an onsite spa at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a pool and an indoor pool. Grab your bathers and lounge poolside while enjoying on a lounger. The pool is open 8 AM to 11 PM.

Is there a free airport shuttle available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG does not offer an airport shuttle service.

What time are check-in & check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in begins at 3:00 PM. Check-out time is 11 AM.

Are pets allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, pets are not allowed.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 778 out of 1001 reviews
Rating 8 - Good. 151 out of 1001 reviews
Rating 6 - Okay. 39 out of 1001 reviews
Rating 4 - Poor. 16 out of 1001 reviews
Rating 2 - Terrible. 17 out of 1001 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Brandon

Stayed 1 night in Nov 2025

10/10 Excellent

Marianne

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very nice with comfy bed. It’s a lovely area. We went to a brewery in town and had pizza, salad and a beer.
Stayed 1 night in Nov 2025

10/10 Excellent

Hollie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great
Stayed 1 night in Oct 2025

10/10 Excellent

Connie

Travelled with family
Liked: Cleanliness, staff & service, amenities
Spacious room, clean, & comfy with everything we needed.
Stayed 1 night in Nov 2025

10/10 Excellent

Bryan

Travelled with family and small children, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent place to stay.
Stayed 1 night in Nov 2025

6/10 Okay

Denise

Business traveller, Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Disliked: Staff & service
When I checked in for some reason I had two rooms booked. While talking to the front desk lady she started yelling at me and was very rude. She needs a new job.
Stayed 1 night in Oct 2025

2/10 Terrible

rick

Stayed 2 nights in Oct 2025

10/10 Excellent

Connie

Stayed 1 night in Oct 2025

6/10 Okay

Gene

Business traveller
Liked: Cleanliness, property conditions & facilities, room comfort
Didnt appreciate finding out upon checking in that the elevators were out of order and all they had was second floor. Couldnt they be upfront about this when booking? So questionable at this price range.
Stayed 1 night in Oct 2025

10/10 Excellent

Gerald

Travelled with family, Travelled with group
Liked: Cleanliness, property conditions & facilities, room comfort
We had a great overnight stay to see SEMO play TSU! The hotel was great! No issues whatsoever.
Stayed 1 night in Oct 2025

10/10 Excellent

Kim

Stayed 1 night in Oct 2025

10/10 Excellent

Vicki

Stayed 1 night in Oct 2025

10/10 Excellent

Sandy

Stayed 2 nights in Sep 2025

10/10 Excellent

Gretchen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe
Stayed 1 night in Oct 2025

10/10 Excellent

Malinda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Oct 2025

10/10 Excellent

Jane

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel staff at checkin very friendly & helpful. Many dining options within walking distance of hotel. Beds comfy and room clean
Stayed 1 night in Oct 2025

4/10 Poor

James E. Askew

Disliked: Cleanliness, property conditions & facilities
The room was dirty and old
Stayed 1 night in Sep 2025

10/10 Excellent

Jerry

Stayed 2 nights in Sep 2025

10/10 Excellent

John Charles

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Excellent
Stayed 2 nights in Sep 2025

10/10 Excellent

David

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great staff and clean rooms.
Stayed 1 night in Sep 2025

8/10 Good

Mark

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The beds were so uncomfortable and the pillows were worse. I did not sleep well. The breakfast buffet was nice, but the sausage was served cold and it gave us all a stomach ache. The whole hotel was very clean and the staff were all very nice. They even gave me a free tooth rush because I had forgotten mine at home.
Stayed 1 night in Sep 2025

8/10 Good

Douglas

Liked: Cleanliness, staff & service, property conditions & facilities
No shuttle service
Stayed 1 night in Sep 2025

10/10 Excellent

Debra

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Everything was wonderful.
Stayed 2 nights in Jul 2025

10/10 Excellent

Cherish

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We got greeted with such a friendly smile and attitude as soon as we got in. The room was clean and roomy. Would highly recommend and come back.
Stayed 1 night in Sep 2025

10/10 Excellent

Lynn

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025