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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Photo gallery for 21C Museum Hotel St Louis

Classic architecture with a grand entrance and evenly spaced windows.
Enjoy a luxurious bar experience with a curved countertop, comfortable seating, and a vibrant mural.
Relax in a classic room with a large pool table, elegant curtains, and a chandelier.
Experience the grandeur of our multi-level atrium, featuring a basketball court and balcony with a railing.
Relax by the pool surrounded by a comfortable seating area and natural light.

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
The current price is NZ$307
includes taxes & fees
31 Aug - 1 Sept

Explore the area

View map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • Busch Stadium
    ‪14 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Separate bath and shower
Private bathroom
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Cozy retreat with a bunk bed, round table, and vibrant artwork.

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Private bathroom
Bathrobes
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Separate bath and shower
Private bathroom
  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Relax in a stylish space with a comfortable bed, armchair, and desk, surrounded by natural light and decorative touches.

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(67 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

Two spacious beds with white linens and multiple pillows, a modern headboard, and a stylish table with a lamp and flowers.

Deluxe Double Room, 2 Queen Beds

8.6 out of 10
Excellent
(19 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Relax in a stylish room with a tufted headboard, green sofa, and brown armchair.

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(23 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Cozy retreat with a neatly made bed, bedside table, and potted plant.

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

Cozy retreat with a neatly made bed, bedside table, and potted plant.

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Two spacious beds with white linens and multiple pillows, a modern headboard, and a stylish table with a lamp and flowers.

Luxury Double Room, 2 Queen Beds

9.0 out of 10
Wonderful
(20 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like City Museum and Enterprise Center. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include St. Louis Union Station and America's Center Convention Complex.

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

Languages

English

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  • Free WiFi
  • Restaurant
  • Air conditioning
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includes taxes & fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 8 Aug 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 31 Aug 2025 start from NZ$298.32, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 931 out of 1290 reviews
Rating 8 - Good. 192 out of 1290 reviews
Rating 6 - Okay. 76 out of 1290 reviews
Rating 4 - Poor. 41 out of 1290 reviews
Rating 2 - Terrible. 50 out of 1290 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

8/10 Good

Lynn, St. Louis

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a very unique and interesting hotel. The art is beautiful as is the whole hotel. We had a corner king and it was plenty of room for 2. The furnishings were artsy and fun. Only complaint was that the pillows weee way too dense and BIG. Not very comfortable for our liking. The bed and sheets were lovely. Other than that we loved our stay. Thank you.
Stayed 1 night in May 2025

10/10 Excellent

Derek

Stayed 1 night in Apr 2025

10/10 Excellent

Margaret

Stayed 1 night in Apr 2025

10/10 Excellent

John

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great gym and pool, fun atmosphere on main level
Stayed 1 night in Apr 2025

8/10 Good

Jerome

Travelled with group
Liked: Cleanliness, property conditions & facilities, room comfort
Stayed 1 night in May 2025

4/10 Poor

John

Travelled with family and small children
Disliked: Staff & service, amenities, property conditions & facilities
I've stayed at 21c in Nashville and fully enjoyed the experience. In St. Louis it's not in a great neighborhood, very run down. The room phone never worked thank got for cell phones and elevators. The temperature controls didn't work properly. Fire alarm went off in the middle of the day while my 3 year old grandson was sleeping my daughter in law had to carry him down ten flights of stairs only to be told it was a mistake alarm. Valet parking is $50 for an open fenced lot across the street??? We walked around one afternoon and never really found anything cool or fun to go do... I would avoid this hotel get something g. Lose to the. Cardinals ball park same pricing with a way better experience!
Stayed 3 nights in Apr 2025

6/10 Okay

Jessica

Travelled with partner
Liked: Cleanliness, amenities
Disliked: Staff & service
Looks good and the toiletries brand is amazing
Stayed 1 night in Apr 2025

10/10 Excellent

Richard, Hickory

Stayed 1 night in Apr 2025

10/10 Excellent

Moe

Stayed 3 nights in Apr 2025

10/10 Excellent

Joni

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular restaurant, comfortable room, good museum, and it feels safe. The elevator has keyed access to each floor.
Stayed 2 nights in Apr 2025

8/10 Good

Fran

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Repeat Customer

This was our 2nd stay which speaks volumes! We love this place. It is upscale but relaxed. Historic but modern. Great location in walking distance of many attractions, but quiet. Clean. So Clean. I feel very comfortable walking around the room without shoes. Just a couple issues I will note...no after hours room service or even vending to get a snack or drink. And, only 1 roll of toilet paper. I think 2 rolls would have made us less nervous.😉
Stayed 1 night in Apr 2025

6/10 Okay

Siegfried

Liked: Cleanliness, amenities, property conditions & facilities
Bar service was very slow. Staff didn’t tell us there was a coffee shop.
Stayed 2 nights in Apr 2025

8/10 Good

Heather

Liked: Cleanliness, property conditions & facilities
This hotel has a lot of potential. It’s in a good area of the city. The hotel itself is so fun bright colored wallpaper art all over the place pool hot tub saunas pool tables literally has something for everybody. The front desk staff was OK. The valet attendant were fantastic all in all enjoyed the trip
Stayed 2 nights in Apr 2025

10/10 Excellent

Elia

Liked: Cleanliness, staff & service, property conditions & facilities
Me gusto mucho la atencion al cliente y el progecionalizmo. Gracias
Stayed 2 nights in Apr 2025

10/10 Excellent

Sandra

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our two nights at this hotel. The property was nice and we were able to walk to Enterprise stadium easily.
Stayed 2 nights in Apr 2025

10/10 Excellent

Hilary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved everything! Will be back!

We will be coming back! We absolutely loved the hotel. From the rooms (we had a Deluxe King Suite) to the restaurants to the huge art museum…it did not disappoint. It was also within walking distance to our event at Enterprise Center. Staff were very friendly. Although we didn’t get in, the pool and hot tub both were large and looked nice. They also have two huge weight/workout rooms, treatment rooms, steam rooms, etc.
Stayed 1 night in Apr 2025

8/10 Good

Kenda

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Andrea, Du Quoin Illinois

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I stayed at this hotel for the stl go marathon and absolutely loved it! Super close to the start/finish so that was convenient. The hotel itself was beautiful and unique. From the art, to the amenities, and staff! Ugh it was all perfect. I will be staying here again next time I’m in town. 10/10!
One of the art galleries
View from the hotel window
Stayed 1 night in Apr 2025

10/10 Excellent

Samuel

Liked: Cleanliness, staff & service, property conditions & facilities
It’s easy to walk to most every venue I go to downtown. The hotel is amazingly beautiful.
Stayed 1 night in Apr 2025

2/10 Terrible

Steve

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort
We checked in the rain, not realizing they didn’t have a car port area or porters with umbrellas. Signage was very confusing outside and inside. The 1st room we were given had no electricity. The second room we were given had stains on the walls, carpet and bedding-which we suspected was mold. There was also someone’s medical patch on the shower floor. When my wife went to look at it closer, the shower floor had disgusting build up of something along the sides. My wife felt sick and we had already gotten ready for bed so when we called about the bed they said house cleaning was gone and we could move to another room by coming back downstairs and going through the same 30 minute process we had already done. Yes we should have checked the room before doing anything, but we’ve never had a boutique hotel that wasn’t more than acceptable. My wife slept in the chair, I slept in my clothes on top of other clothes on top of the bedding. The elevator appeared to have wine thrown all over it when we checked in, but was cleaned in the morning. They did refund the additional two nights we were scheduled to stay in, so I’m thankful for that. But we were told the one night “stay” would also be refunded which didn’t happen. This was one of the worst experiences I’ve had in my significant travel history.
Stayed 2 nights in Apr 2025

8/10 Good

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Great place in St. Louis.
Stayed 1 night in Apr 2025

10/10 Excellent

Kenneth

Liked: Cleanliness, staff & service, property conditions & facilities
No parking except valet
Stayed 1 night in Apr 2025

10/10 Excellent

Eric

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a really nice place to stay. Me and my wife enjoyed the hotel, pool, dinning, and the staff. We are going to go back. hopfuly for my birthday. Thank you hotel 21c!
Stayed 2 nights in Apr 2025

10/10 Excellent

Michelle

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing
Stayed 2 nights in Apr 2025

10/10 Excellent

Emily

Travelled with family
Liked: Staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Apr 2025