21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Photo gallery for 21C Museum Hotel St Louis

Interior
Dining
Loft, 2 Queen Beds
Billiards
Exterior

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
The current price is NZ$281
includes taxes & fees
29 Dec - 30 Dec

Explore the area

View map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, City Museum
    ‪6 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(78 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Bathrobes
Shower/bath combination
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Hairdryer
Bathrobes
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Bathrobes
Separate bath and shower
  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Bathrobes
Separate bath and shower
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Private bathroom
  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like City Museum and Enterprise Center. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include St. Louis Union Station and America's Center Convention Complex.

What's nearby

  • Washington Avenue Historic District - 3 min walk - 0.3 km
  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • St. Louis Aquarium at Union Station - 9 min walk - 0.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Medina Grill - ‬5 min walk
  • ‪White Knight Diner - ‬4 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Idol Wolf - ‬1 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)
  • Limited on-site valet parking

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 23 Dec 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 29 Dec 2025 start from NZ$272.36, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

Is there a golf course on site at 21C Museum Hotel St Louis ?

There isn't one on site, but St. Louis Union Station Mini Golf is a short 13-minute walk away.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1087 out of 1509 reviews
Rating 8 - Good. 225 out of 1509 reviews
Rating 6 - Okay. 97 out of 1509 reviews
Rating 4 - Poor. 46 out of 1509 reviews
Rating 2 - Terrible. 54 out of 1509 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

2/10 Terrible

John

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort

Common Areas Are Nice; Hotel Not Worth Your Time

I wanted to like the 21c Museum Hotel St. Louis, but my stay was disappointing from start to finish. I was moved twice; the first room had a bathroom issue; the second (promised as the same type) was noticeably smaller. I was then placed in a suite that had a strong, unpleasant odor, which I tolerated only because I was exhausted from the room changes. Common areas didn’t help: elevators were not clean, and despite requesting service, housekeeping didn’t arrive until almost 7pm. While the bar staff and one front-desk attendant were friendly, several others were curt and unhelpful. Most concerning, a staff member, likely maintenance, tried to enter my room before checkout without knocking and offered only a half-hearted apology when he saw me. I was told the first night would be refunded, but Hotels.com had no record of a refund request from the property. I had planned to return for Thanksgiving and had already booked, but I’ve since canceled. Overall, this was a poor experience marked by inconsistent service, cleanliness issues, and a lack of accountability.
Stayed 3 nights in Sep 2025

6/10 Okay

Kelly

Liked: Staff & service

Beautiful design, lacking maintenance

You can tell that there was a lot of care that went into the design and creation of this hotel, but unfortunately, there has been a lack of maintenance that erodes the overall experience. The Good: - The Museum is well curated, thoughtfully presented, and inspired. We really enjoyed each exhibit. - Idol Wolf and Good Press are both high-quality restaurants, and we enjoyed the food and service at each. The portion sizes and ingredients were both above our expectations for a hotel restaurant. The Bad: - While the rooms are clean, there was a general lack of maintenance for the most basic needs for a hotel guest. For example, our shampoo and body wash were both ripped off the wall, and rather than being repaired, the broken bottles were just placed in the shower. We needed to call the front desk in order to receive functioning toiletries, which was disappointing given the price of our nightly stay. - While a small detail, we were only provided one coffee cup in our room. A great coffee maker can only be enjoyed if we have a cup to drink out of, and it underlined the lack of attention to detail we had seen in other parts of our stay. - The pool and locker rooms were very poorly maintained and frankly dirty. Towels were not consistently available (only in the women's locker room), the shower grout was visibly moldy, and there was a lack of general maintenance in what clearly was a previously beautiful pool and spa area. Overall, the experience was fine, but below expectations.
Stayed 1 night in Sep 2025

10/10 Excellent

JeTaun

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My stay was nice and comfortable. The staff was very courteous
Stayed 3 nights in Sep 2025

10/10 Excellent

martin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Connie

Travelled with group
Liked: Cleanliness, amenities, property conditions & facilities
Great place to stay. Will definitely stay here next time I’m in st. Luis
Stayed 1 night in Sep 2025

10/10 Excellent

Sabrina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Renean

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Sep 2025

10/10 Excellent

Fred

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Sep 2025

10/10 Excellent

Connie

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great experience!
Stayed 1 night in Sep 2025

10/10 Excellent

marie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

2/10 Terrible

Angie

Disliked: Cleanliness, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Alex

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Sep 2025

10/10 Excellent

Whitney

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful stay!
Stayed 1 night in Sep 2025

8/10 Good

Jeffrey, Springfield

Travelled with partner
The restaurant and coffee shop servers and valets were great- others seemed to be quiet quitting and disinterested
Stayed 2 nights in Sep 2025

8/10 Good

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Didn't have our room ready until after check in time advertised..
Stayed 1 night in Sep 2025

6/10 Okay

Blake D.

This is not the luxury hotel I expected. From the moment I walked in I see that it doesn’t look anyone has vacuumed for a week. Walls are banged up and in need of paint. Area not great either. Would not choose again
Stayed 1 night in Sep 2025

10/10 Excellent

Catherine

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jun 2025

6/10 Okay

Chante

Travelled with family
Liked: Cleanliness
Disliked: Amenities, property conditions & facilities
Valet was rude, tv did not work and when we called, they said they’d send someone up to fix it and did not, the AC did not work either. Also there were hairs in the shower that were there when we checked in. Will not be staying here again.
Stayed 1 night in Sep 2025

10/10 Excellent

Blane

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent

Beautiful hotel. I loved the art museum. The restaurant was really great. The gym and pool were amazing. I highly recommend.
Stayed 2 nights in Sep 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Get away trip with bae

It was nice. Great amenities and lots to do. I loved the museum
Stayed 2 nights in Sep 2025

6/10 Okay

Nicole

Travelled with group
Disliked: Staff & service
An okay area. Our body was was never refilled and when asking about early check in I spoke with 3 different people who all told me different things.
Stayed 2 nights in Sep 2025

10/10 Excellent

Leslie

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel in a historic YMCA building downtown. First class interiors, art collection, ambiance, and rooms. The room was small but well appointed. Very quiet. All amenities (no microwave), including wonderful Italian coffee machine. We also had an amazing cocktail hour with the bartender in the lobby. He knows his craft very well. We’ll be starting here often in the future.
Stayed 2 nights in Sep 2025

10/10 Excellent

Casey

Liked: Amenities, property conditions & facilities
Amazing staff, clean!
Stayed 1 night in Sep 2025

10/10 Excellent

Marquis

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Sep 2025

10/10 Excellent

Stephen

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Very interesting property. Enjoyed the stay.
Stayed 1 night in Sep 2025