21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Photo gallery for 21C Museum Hotel St Louis

Exterior
Bar (on property)
Indoor pool
1 bedroom, in-room safe, desk, laptop workspace
Room, 1 King Bed, Corner

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
The current price is NZ$303
includes taxes & fees
29 June - 30 June

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • City Museum
    ‪6 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Room (Bunk Bed)

8.0 out of 10
Very good
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 Single Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(56 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 Double Bed

Deluxe Double Room, 2 Queen Beds

8.2 out of 10
Very good
(16 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Bathrobes
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(19 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Luxury Double Room, 2 Queen Beds

8.8 out of 10
Excellent
(15 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Bathrobes
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like Enterprise Center and City Museum. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include St. Louis Union Station and America's Center Convention Complex.

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

Languages

English

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 24 Jun 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 29 Jun 2025 start from NZ$294.98, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 862 out of 1193 reviews
Rating 8 - Good. 181 out of 1193 reviews
Rating 6 - Okay. 67 out of 1193 reviews
Rating 4 - Poor. 37 out of 1193 reviews
Rating 2 - Terrible. 46 out of 1193 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Mark, Bloomington

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I have stayed at 21C hitels before, but never this one in St. Louis. The facility is beautiful! Our room was very clean, and the bathroom was huge! The amenities here are wonderful. The pool is beautiful, and the hot tub is huge. The check in process was smooth and quick, and we got a very early check in. The gentleman at the front desk was very accommodating and especially cordial. The only downfall was the neighborhood. That, however, is not a hotel problem, but a St. Louis issue. I always forget how dead the St. Louis downtown is unless there's a Cardinal baseball game scheduled. Walking through a pretty dark and desolate downtown to get back to the hotel late at night is concerning. I walk all over downtown Chicago at all hours and never feel unsafe, but I dont have the same confidence in downtown St. Louis.
Stayed 1 night in Mar 2025

6/10 Okay

Ashley

Travelled with family
Liked: Room comfort

Cool, but quite a few misses in my opinion

The hotel is in a good spot close to union station activities and everything else is 10min away which isn’t a bad drive. Loved that it was artsy and cute decor. Cute bar inside. Did not have enough time to experience restaurant but the menu sounded good. The fitness spa area is a nice accommodation and visiting the art free museum associated with hotel was nice to bum around. My stars were due to walking in not feeling like the staff was very accommodating and acted annoyed with me and eachother so that was different. Just weird attitudes kind of cool kids not really great concierges. But, Finding street parking was easy on a weekend so appreciated that. But, they are limited in carts and The elevators were all broken except one so that took forever. Room appeared semi clean. They left only a 1/4 used toilet paper roll and a few tissues back in tissue box. Just odd. So the staff didn’t even restock and there was food and drinks left in the fridge from previous people. So I felt like it was “fake” cleaned. There was a wad of hair on our bed and in the bathtub it had another wad of a dust bunny. The coffee machine would have been great but they didn’t stock any cups. Maybe they were trying to encourage you to go to their coffee shop. Which I did and it was good and the staff there were probably the most with the program. It was fine. I’d come back to try their Spanish restaurant but would probably stay elsewhere with my family next time. We did all like the decor in hotel
Stayed 2 nights in Mar 2025

10/10 Excellent

Jeremy

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
To start off the valet was amazing and the staff was great. The bartenders were on point and our waiter was very helpful too. The little coffee shop was great for a quick breakfast and the robes were like a hug from your loved one. Room were really cool with an older feel yet modern. The gallery was very unique and loved all the amenities. Only thing I would say I didn’t like was the pillows on the bed. But all in all would definitely stay again if ever in St Louis.
Stayed 2 nights in Mar 2025

8/10 Good

James

Stayed 1 night in Jan 2025

10/10 Excellent

Colleen

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Welcoming, kind staff. So enjoyed our stay.
Stayed 2 nights in Mar 2025

10/10 Excellent

Nyna

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel is fantastic. All in one entertainment with the museum combined. Very clean and nice staff.
Stayed 1 night in Mar 2025

8/10 Good

Nathalie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Mar 2025

10/10 Excellent

Toni

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

6/10 Okay

Arron

Business traveller
Liked: Staff & service, amenities
Disliked: Cleanliness, property conditions & facilities
I’ve been visiting St. Louis for over 12 years and used to try different hotels — until I stayed at 21c. Since that first visit, I haven’t stayed anywhere else. It had a fresh energy, a unique atmosphere, and the kind of people that made it feel exciting. The real standout has always been the staff, especially the bar and restaurant team — people like Carson, Cam, and JoJo. Their effort, warmth, and attention to detail make every stay feel like more than just a hotel visit. Over time, they’ve become familiar faces and genuine friends. But on my most recent stay, I was let down — not by them, but by housekeeping and management. My room simply wasn’t clean: mould in the shower, someone else’s hair, stains left untouched, and amenities not replaced. Once you see it, you start noticing more — and unfortunately, I did. I raised it with the team (not even their job to fix) and they went out of their way to make things right — offering a credit and even leaving a bottle of their own gin in my room. Lovely gestures, truly appreciated — but the mould was still there the next day. The issue wasn’t fixed. For a short stay, I’d still recommend it. But for anything longer, if you value cleanliness and comfort, I’d think twice. The team out front are brilliant — but they’re being let down by what’s happening behind the scenes.
Stayed 9 nights in Mar 2025

10/10 Excellent

Steve

Stayed 1 night in Mar 2025

8/10 Good

JANA

Travelled with group
Liked: Staff & service, amenities, property conditions & facilities
The property is very special, with a historic and totally renovated pool and spa, and a large art exhibit. The bar and lobby are loaded with art and beautifully designed surroundings. Only one of three elevators were working this week, so a lot of waiting and frankly feeling unsafe. The breakfast restaurant is good. There is no lunch option and the front desk has zero intel regarding outside options. The dinner menu is ridiculously expensive and not very enticing. Drinks are crazy expensive ($14 for 3 oz of sav blanc) The valet is $45/night in kind of a rundown, crummy neighborhood.
Stayed 2 nights in Mar 2025

10/10 Excellent

Veronica

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful hotel. Amazing indoor pool. My kids Loved the bunk beds.
Stayed 2 nights in Mar 2025

10/10 Excellent

Rebecca

Travelled with partner
Liked: Amenities
We stayed here for a night while we were in town to watch the Blues. It's close enough to walk to the stadium or take a quick uber. It was close to union station too. Wonderful hotel! We will be back.
Stayed 1 night in Mar 2025

10/10 Excellent

Jocelynne

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Mar 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great
Stayed 1 night in Feb 2025

10/10 Excellent

Christopher

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Mar 2025

10/10 Excellent

Ashley

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Tracey

Travelled with family, Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We had a couple of hurdles when we arrived and the staff was so kind and went out of their way to make it right. I would recommend this place to anyone and will definitely stay here again. Kind people make everything else seem so minor. I appreciate everyone I have come in contact with during this stay!
Stayed 1 night in Mar 2025

2/10 Terrible

Deborah

Liked: Cleanliness, property conditions & facilities
Stayed 1 night in Mar 2025

10/10 Excellent

Alexus

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

8/10 Good

Ju Hui

Stayed 2 nights in Mar 2025

10/10 Excellent

Bryan

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Great boutique hotel in downtown St. Louis, the hotel was busy when we checked in and the front desk staff was a bit harried, but they gave us the essential information we needed. The art gallery on the second floor was a great addition to our stay, as was the on sight restaurant, The Idol Wolf, amazing food, and service. The hotel itself has a very cool, and eclectic vibe, but is beginning to look a little “run down”. But overall a good experience, we will definitely stay here again if we are ever in the area.
Stayed 1 night in Mar 2025

10/10 Excellent

Lisa

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

chastity

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really clean and updated. The museum on the 2nd floor was nice to browse. Valet guys were funny and friendly. The gal at check in was not as friendly. Would stay here again for convenience to concerts, sporting events, etc.
Stayed 1 night in Mar 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

March 21c couples stay

The hotel, bar, restaurants and art were amazing. Would definitely stay here again. Some improvements; need a hair dryer in room without asking, need hooks in bathroom and need higher quality toilet paper.
Stayed 2 nights in Mar 2025