21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Photo gallery for 21C Museum Hotel St Louis

Exterior
Bar (on property)
Interior
Indoor pool
Billiards

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
The current price is NZ$310
includes taxes & fees
28 Sept - 29 Sept

Explore the area

View map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • Busch Stadium
    ‪14 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Separate bath and shower
Private bathroom
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Separate bath and shower
Private bathroom
  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(74 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

Deluxe Double Room, 2 Queen Beds

8.6 out of 10
Excellent
(20 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Private bathroom
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(25 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(21 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Private bathroom
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

You may also like

About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like City Museum and Enterprise Center. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include St. Louis Union Station and America's Center Convention Complex.

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪White Knight Diner - ‬4 min walk
  • ‪Idol Wolf - ‬1 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 22 Sept 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 28 Sept 2025 start from NZ$301.43, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

Reviews

21C Museum Hotel St Louis Reviews

9.0

Wonderful

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness
Rating 10 - Excellent. 998 out of 1381 reviews
Rating 8 - Good. 204 out of 1381 reviews
Rating 6 - Okay. 86 out of 1381 reviews
Rating 4 - Poor. 42 out of 1381 reviews
Rating 2 - Terrible. 51 out of 1381 reviews

Reviews

2/10 Terrible

Gilles, Tabuk

Travelled with family
Disliked: Cleanliness, amenities
It is a museum hotel, but the museum is currently closed. Arrived at 6:30 PM with check-in at 3, and the room took 1.5 hours to be ready. We were given the room, but it was not clean, and the bathrobes were stained. The garbage in the bathroom was not empty. Their best proposal was to try to downgrade us from the suite we booked to a king. Service hote. We spent 2 nights and there was no night service to make the bed in the morning. What a shame.
Stayed 2 nights in Jun 2025

10/10 Excellent

Jason

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jun 2025

10/10 Excellent

Denise

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jun 2025

10/10 Excellent

James

Stayed 1 night in Jun 2025

2/10 Terrible

Adam

Stayed 3 nights in Jun 2025

10/10 Excellent

Kyler

Liked: Cleanliness, property conditions & facilities
Stayed 2 nights in May 2025

10/10 Excellent

Caitlin

Stayed 1 night in Jun 2025

10/10 Excellent

Allen

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We liked that the hotel had valet parking, which made it easier than trying to find a spot to park. We drove a larger van, and trying to find a spot to park would have been hard. The hotel had a great pool and hot tub. The rooms were great, clean and comfortable.
Stayed 1 night in Jun 2025

10/10 Excellent

Lima Rose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay
Stayed 1 night in Jun 2025

10/10 Excellent

Luis, Southaven

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent service of everyone in the hotel. Please don’t change and continue with excellent services.
Stayed 1 night in Jun 2025

10/10 Excellent

Juanita

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in May 2025

10/10 Excellent

Jonathan

Stayed 2 nights in Jun 2025

10/10 Excellent

Shantelle

Stayed 3 nights in May 2025

10/10 Excellent

Meagan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
This hotel was beautiful and fun. Super easy to walk to the r Center. The room was very modern, but pretty tiny. I wouldn’t want to need to spend a lot of time there. It was perfect for an overnight stay to attend a concert. The restaurants were food. We did dinner and breakfast. Not many food options within walking distance. We really liked the water bottles and refill stations and the pool was unique and quirky.
Stayed 1 night in Mar 2025

10/10 Excellent

Kenyatta

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
This property was a wonderful place to stay. Even though the museum in side was booked two of the three days I was there. I got a chance to see it before heading home.
Stayed 2 nights in Jun 2025

10/10 Excellent

Hasani

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
The pool and patio area was beautiful. Everything including the staff was 10/10.
Stayed 2 nights in Jun 2025

10/10 Excellent

Hillary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Amazing stay! Best hotel bar ever!!!
Stayed 3 nights in Jun 2025

10/10 Excellent

Akeya

Stayed 1 night in Apr 2025

4/10 Poor

jessica

Liked: Room comfort
Disliked: Staff & service
only options for parking were a paid spot behind the hotel unsupervised for $25 a night or valet that is supposed to be protected for $50 a night. the only difference between the two is valet is a fenced in parking area across the street from the hotel. Ball from our trucks hitch was stolen, among other marks and scratches that we noticed. we also noticed the valet keeps everyones keys in a locked box in-front of the hotel, not secure. the hotel itself is very pretty, but the lack of knowledge given about the amenities to the guests is crazy. the rooms are nice though they are not cleaned as well as they should’ve been. housekeeping came once in our 2 night stay and they did not change the trash or replenish the towels. the phone in the room did not work. the mini fridge was leaking (front desk was alerted and they said someone would be in that night but never came). the first night a fire alarm went off alerting all the guests to exit the building. the alarm turned off a few minutes after and then came back on, the whole time the staff was not alerting the guests of what was happening. the second night our room lights didn’t come on after hitting the switch for at least 10 minutes. we ordered room service, the bill was $165. the food came up cold, the steak was bland and the lamb meal was tiny for the price. the wine we ordered came up still corked with no way to uncork it. due to the phone not working, resolving this small issue was more difficult then it should have been.
Stayed 2 nights in Jun 2025

8/10 Good

Angela

Travelled with partner
Liked: Property conditions & facilities
I did not receive the room I booked. They did not notify me beforehand or at check in that it was unavailable. After going back down to the desk to inquire, they did offer a credit for use at breakfast.
Stayed 1 night in Jun 2025

10/10 Excellent

roland

Liked: Cleanliness, staff & service, property conditions & facilities
Very good
Stayed 1 night in Jun 2025

4/10 Poor

Terra

Travelled with partner
Disliked: Cleanliness, staff & service, property conditions & facilities
Our sheets had a huge yellow stain on them, found a cockroach running around the dinning room/bar. Our room AC would not kick on and cool down at night. And We stayed there ro virw the art museum, which the closed for private events.
Stayed 2 nights in Jun 2025

10/10 Excellent

Kristie

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great art all over and access to the galleries was a neat experience. Tim was clean and comfortable.
Stayed 1 night in Jun 2025

10/10 Excellent

Niki

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It’s our 2nd time staying and we love the hotel…. The front desk, cafe, valet & hotel staff are fantastic. 21C Museum Bar needs to work on their bartenders…. We went to the bar @ 5:30 PM before heading to our concert Saturday night to get a couple cocktails and sat for 10 minutes… CRICKETS! We got & left without an anyone acknowledging us. Lost out on an easy sale! Still love the hotel!
Stayed 2 nights in Jun 2025

10/10 Excellent

Sean

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Jun 2025