
American Airlines Flights from Detroit (DTW) to San Diego (SAN)
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American Airlines Flights from DTW to SAN
How much is a American Airlines flight from Detroit (DTW) to San Diego (SAN)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Detroit (DTW) to San Diego (SAN) are there per day?
American Airlines flies flights direct every day between Detroit (DTW) and San Diego (SAN).
How far is Detroit (DTW) from San Diego (SAN)?
It’s from Detroit (DTW) to San Diego (SAN).
What is the best airline to fly from Detroit Metropolitan Wayne County?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Detroit Metropolitan Wayne County with: .
Can I change or cancel my American Airlines tickets from Detroit to San Diego on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Detroit (DTW) to San Diego (SAN)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Detroit. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Detroit to San Diego?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Detroit (DTW) to San Diego (SAN)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from DTW to SAN?
It typically takes hours to fly directly from Detroit (DTW) to San Diego (SAN).
Epic Hotel in San Diego

Sheraton San Diego Resort
Love how clean it was and spacious
Reviewed on 11 Mar 2026

The DEXTRO Little Italy, BW Premier Collection
Lovely newly updated rooms, wonderful staff, superb value- thank you for an excellent stay!
Reviewed on 11 Mar 2026

Wyndham San Diego Bayside
Room was dirty and AC was broken. They gave us a new room after we spoke with them. Then we went to open the door to the new room and heard people talking as I grabbed the door handle, two men walked out. I complained to the manager and he started arguing with me. This place has really gone down ...
Reviewed on 12 Mar 2026
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^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.