La Mesa Holiday Packages

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Let us bundle your hotels and flights into a tidy little package.

With the extra money you can experience more in La Mesa.

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La Mesa Accommodation

Our database lists 34 accommodation in La Mesa. However, none of them are located directly in the centre. Have a look through your options on Wotif — you're sure to find a great place not too far away.

Searching for somewhere to sleep? No worries — we've got it covered. The Vineyard Hacienda (12685 Campo Rd) and the Holiday Inn Express San Diego South - National City (1645 E Plaza Blvd) both have top reviews and a convenient location.

Car Hire in La Mesa

If you don't have even a minute to lose, the smartest option is to rent a car directly from San Diego International Airport. Economy Rent a car is located near the arrivals area.

There's no need to stress out over hire cars here. Enterprise (8363 Centre Drive, Suite 6H) is our hot tip for this area and is only 2 kilometres from the middle of town.

Holidays to La Mesa

Got a thing for going places you've never visited before? Likewise. But there's no need to get lost in the process. Have a snoop through our guide to La Mesa and you'll be sauntering around like a real local in no time.

The San Diego County neighbourhood of La Mesa sits 16 kilometres from all the excitement of the centre. You'll discover it in the city's east.

If curiosity's your middle name, you'll probably want to learn a few bits of trivia about San Diego County — like how many people call it their home. Well, at last count the population was 1 300 000.

Top La Mesa hotels

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$185 per night from 1 Dec to 2 Dec
NZ$185
1 Dec - 2 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
"Very easy nice hotel. Only complaint is the rooms are much smaller than expected. However the pool and hottub area is so nice that it truly makes up for this as you’ll spend more time at the pool than the rooms"

Reviewed on 11 Nov 2026

Opens in a new windowHandlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$350 per night from 22 Nov to 23 Nov
NZ$350
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Opens in a new windowWyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$422 per night from 22 Nov to 23 Nov
NZ$422
22 Nov - 23 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
Opens in a new windowHard Rock Hotel San Diego
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