
American Airlines Flights from Buffalo (BUF) to San Diego (SAN)
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American Airlines Flights from BUF to SAN
How much is a American Airlines flight from Buffalo (BUF) to San Diego (SAN)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Buffalo (BUF) to San Diego (SAN) are there per day?
American Airlines flies flights direct every day between Buffalo (BUF) and San Diego (SAN).
How far is Buffalo (BUF) from San Diego (SAN)?
It’s from Buffalo (BUF) to San Diego (SAN).
What is the best airline to fly from Buffalo Niagara Intl.?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Buffalo Niagara Intl. with: .
Can I change or cancel my American Airlines tickets from Buffalo to San Diego on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Buffalo (BUF) to San Diego (SAN)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Buffalo. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Buffalo to San Diego?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Buffalo (BUF) to San Diego (SAN)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from BUF to SAN?
It typically takes hours to fly directly from Buffalo (BUF) to San Diego (SAN).
Epic Hotel in San Diego

Sheraton San Diego Resort
I had a very disappointing stay. Housekeeping only made the bed—there was no actual cleaning or vacuuming done at any point during my visit. Despite making multiple requests for towels, none were ever delivered. To make matters worse, the shampoo and soap bottles were empty, the washroom floor remained ...
Reviewed on 3 Apr 2026

Wyndham San Diego Bayside
Yes it was great. I was just confused why my parking cost $50 but my card was charged $84 without my knowledge. The deposit of 100 was supposed to be refunded back to me but I got charged $84 in total.
Reviewed on 2 Apr 2026

Homewood Suites by Hilton San Diego Airport/Liberty Station
Clean room friendly staff. Very nice stay!!
Reviewed on 3 Apr 2026
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^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.