American Airlines Flights from St. Louis (STL) to San Francisco (SFO)
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American Airlines Flights from STL to SFO
How much is a American Airlines flight from St. Louis (STL) to San Francisco (SFO)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from St. Louis (STL) to San Francisco (SFO) are there per day?
American Airlines flies flights direct every day between St. Louis (STL) and San Francisco (SFO).
How far is St. Louis (STL) from San Francisco (SFO)?
It’s from St. Louis (STL) to San Francisco (SFO).
What is the best airline to fly from Lambert-St. Louis Intl.?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Lambert-St. Louis Intl. with: .
Can I change or cancel my American Airlines tickets from St. Louis to San Francisco on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from St. Louis (STL) to San Francisco (SFO)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from St. Louis. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from St. Louis to San Francisco?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from St. Louis (STL) to San Francisco (SFO)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from STL to SFO?
It typically takes hours to fly directly from St. Louis (STL) to San Francisco (SFO).
Epic Hotel in San Francisco
SFO El Rancho Inn SureStay Collection by Best Western
Yes
Reviewed on 2 Nov 2025
La Quinta Inn & Suites by Wyndham San Francisco Airport West
Room was great. No complaints at all.
Reviewed on 1 Nov 2025
Aloft San Francisco Airport
The staff was courteous and the rooms were clean. The proximity to the airport was key as well.
Reviewed on 2 Nov 2025
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Domestic to International Routes
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Domestic Routes
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^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.