American Airlines Flights from Islip (ISP) to San Diego (SAN)
Change your flight without a fee on select flights
Money Saving Bundle when you purchase Hotel + Flight!
Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app
American Airlines Flights from ISP to SAN
How much is a American Airlines flight from Islip (ISP) to San Diego (SAN)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Islip (ISP) to San Diego (SAN) are there per day?
American Airlines flies flights direct every day between Islip (ISP) and San Diego (SAN).
How far is Islip (ISP) from San Diego (SAN)?
It’s from Islip (ISP) to San Diego (SAN).
What is the best airline to fly from MacArthur?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from MacArthur with: .
Can I change or cancel my American Airlines tickets from Islip to San Diego on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Islip (ISP) to San Diego (SAN)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Islip. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Islip to San Diego?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Islip (ISP) to San Diego (SAN)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from ISP to SAN?
It typically takes hours to fly directly from Islip (ISP) to San Diego (SAN).
Epic Hotel in San Diego
Sheraton San Diego Resort
Love how clean it was and spacious
Reviewed on 11 Mar 2026
The DEXTRO Little Italy, BW Premier Collection
Awesome for everything we really enjoyed our stay. Parking was close and easy. Rooms clean and easy to locate we love your security card for elevator and parking area. And hotel was close to every thing restaurants parks and FWY. 😊
Reviewed on 12 Mar 2026
Wyndham San Diego Bayside
Room was dirty and AC was broken. They gave us a new room after we spoke with them. Then we went to open the door to the new room and heard people talking as I grabbed the door handle, two men walked out. I complained to the manager and he started arguing with me. This place has really gone down ...
Reviewed on 12 Mar 2026
Discover top hotels, vacation package, cheap car rental deals and more with Wotif!
More Destinations
- Aeromexico León (BJX) to San Diego (SAN) flights
- Air Canada Charlottetown (YYG) to San Diego (SAN) flights
- Alaska Airlines Jackson Hole (JAC) to San Diego (SAN) flights
- Alaska Airlines Seattle Paine Field Intl. Airport (PAE) to San Diego (SAN) flights
- Alaska Airlines Tucson (TUS) to San Diego (SAN) flights
- American Airlines Bozeman (BZN) to San Diego (SAN) flights
- American Airlines Cedar Rapids (CID) to San Diego (SAN) flights
- American Airlines Eugene (EUG) to San Diego (SAN) flights
- American Airlines Huntsville (HSV) to San Diego (SAN) flights
- American Airlines Fayetteville (XNA) to San Diego (SAN) flights
- American Airlines Greenville (PGV) to San Diego (SAN) flights
- American Airlines Marquette (MQT) to San Diego (SAN) flights
- American Airlines Shreveport (SHV) to San Diego (SAN) flights
- American Airlines Vienna (VIE) to San Diego (SAN) flights
- Asiana Airlines Seoul (ICN) to San Diego (SAN) flights
- Delta Las Vegas (LAS) to San Diego (SAN) flights
- Delta St. George's (BDA) to San Diego (SAN) flights
- Delta Myrtle Beach (MYR) to San Diego (SAN) flights
- Delta Norfolk (ORF) to San Diego (SAN) flights
- Delta Shanghai (PVG) to San Diego (SAN) flights
- Fiji Airways Brisbane (BNE) to San Diego (SAN) flights
- Jetblue Airways Rochester (ROC) to San Diego (SAN) flights
- Korean Air Vancouver (YVR) to San Diego (SAN) flights
- Lot-Polish Airlines Wroclaw (WRO) to San Diego (SAN) flights
- Lot-Polish Airlines Poznan (POZ) to San Diego (SAN) flights
- Singapore Airlines Brisbane (BNE) to San Diego (SAN) flights
- Swiss International Air Lines Athens (ATH) to San Diego (SAN) flights
- United Gulfport (GPT) to San Diego (SAN) flights
- United Muskegon (MKG) to San Diego (SAN) flights
- United San Pedro Sula (SAP) to San Diego (SAN) flights
- Flights from Acapulco (ACA) to San Diego (SAN)
- Flights from Adana (ADA) to San Diego (SAN)
- Flights from Auckland (AKL) to San Diego (SAN)
- Flights from Albany (ALH) to San Diego (SAN)
- Flights from Anchorage (ANC) to San Diego (SAN)
- Flights from Blenheim (BHE) to San Diego (SAN)
- Flights from Bangkok (BKK) to San Diego (SAN)
- Flights from Busselton (BQB) to San Diego (SAN)
- Flights from Baltimore (BWI) to San Diego (SAN)
- Flights from Bozeman (BZN) to San Diego (SAN)
- Flights from Paris (CDG) to San Diego (SAN)
- Flights from Cleveland (CLE) to San Diego (SAN)
- Flights from Corpus Christi (CRP) to San Diego (SAN)
- Flights from Cincinnati (CVG) to San Diego (SAN)
- Flights from Carnarvon (CVQ) to San Diego (SAN)
- Flights from Dallas (DAL) to San Diego (SAN)
- Flights from Dallas (DFW) to San Diego (SAN)
- Flights from Mudgee (DGE) to San Diego (SAN)
- Flights from Durango (DRO) to San Diego (SAN)
- Flights from Elcho Island (ELC) to San Diego (SAN)
- Flights from Esperance (EPR) to San Diego (SAN)
- Flights from Erie (ERI) to San Diego (SAN)
- Flights from Newark Liberty Intl. Airport (EWR) to San Diego (SAN)
- Flights from Spokane (GEG) to San Diego (SAN)
- Flights from Grafton (GFN) to San Diego (SAN)
- Flights from Gladstone (GLT) to San Diego (SAN)
- Flights from Geneva (GVA) to San Diego (SAN)
- Flights from Hobart (HBA) to San Diego (SAN)
- Flights from Huntsville (HSV) to San Diego (SAN)
- Flights from Houston (IAH) to San Diego (SAN)
- Flights from Indianapolis (IND) to San Diego (SAN)
- Flights from Mount Isa (ISA) to San Diego (SAN)
- Flights from Kalgoorlie - Boulder (KGI) to San Diego (SAN)
- Flights from King Island (KNS) to San Diego (SAN)
- Flights from Kununurra (KNX) to San Diego (SAN)
- Flights from Karratha (KTA) to San Diego (SAN)
- Flights from Kuala Lumpur (KUL) to San Diego (SAN)
- Flights from London (LHR) to San Diego (SAN)
- Flights from Launceston (LST) to San Diego (SAN)
- Flights from Lyon (LYS) to San Diego (SAN)
- Flights from Madrid (MAD) to San Diego (SAN)
- Flights from Medellín (MDE) to San Diego (SAN)
- Flights from Melbourne (MEL) to San Diego (SAN)
- Flights from Memphis (MEM) to San Diego (SAN)
- Flights from Mexico City (MEX) to San Diego (SAN)
- Flights from Medford (MFR) to San Diego (SAN)
- Flights from Miami (MIA) to San Diego (SAN)
- Flights from Mackay (MKY) to San Diego (SAN)
- Flights from Monroe (MLU) to San Diego (SAN)
- Flights from Moranbah (MOV) to San Diego (SAN)
- Flights from Myrtle Beach (MYR) to San Diego (SAN)
- Flights from Newcastle (NTL) to San Diego (SAN)
- Flights from Orange (OAG) to San Diego (SAN)
- Flights from Seattle Paine Field Intl. Airport (PAE) to San Diego (SAN)
- Flights from Proserpine (PPP) to San Diego (SAN)
- Flights from Puerto Vallarta (PVR) to San Diego (SAN)
- Flights from Rockhampton (ROK) to San Diego (SAN)
- Flights from Savannah (SAV) to San Diego (SAN)
- Flights from Louisville (SDF) to San Diego (SAN)
- Flights from Singapore (SIN) to San Diego (SAN)
- Flights from San José del Cabo (SJD) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (SAN)
- Flights from Santa Rosa (STS) to San Diego (SAN)
- Flights from Townsville (TSV) to San Diego (SAN)
- Flights from Trenton (TTN) to San Diego (SAN)
- Flights from Weipa (WEI) to San Diego (SAN)
- Flights from Regina (YQR) to San Diego (SAN)
- Flights from Queenstown (ZQN) to San Diego (SAN)
- Flights from Zürich (ZRH) to San Diego (SAN)
^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.