American Airlines Flights from Portland (PDX) to San Diego (SAN)
Change your flight without a fee on select flights
Money Saving Bundle when you purchase Hotel + Flight!
Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app
American Airlines Flights from PDX to SAN
How much is a American Airlines flight from Portland (PDX) to San Diego (SAN)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Portland (PDX) to San Diego (SAN) are there per day?
American Airlines flies flights direct every day between Portland (PDX) and San Diego (SAN).
How far is Portland (PDX) from San Diego (SAN)?
It’s from Portland (PDX) to San Diego (SAN).
What is the best airline to fly from Portland Intl.?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Portland Intl. with: .
Can I change or cancel my American Airlines tickets from Portland to San Diego on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Portland (PDX) to San Diego (SAN)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Portland. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Portland to San Diego?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Portland (PDX) to San Diego (SAN)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from PDX to SAN?
It typically takes hours to fly directly from Portland (PDX) to San Diego (SAN).
Epic Hotel in San Diego
Sheraton San Diego Resort
Love how clean it was and spacious
Reviewed on 11 Mar 2026
The DEXTRO Little Italy, BW Premier Collection
Awesome for everything we really enjoyed our stay. Parking was close and easy. Rooms clean and easy to locate we love your security card for elevator and parking area. And hotel was close to every thing restaurants parks and FWY. 😊
Reviewed on 12 Mar 2026
Wyndham San Diego Bayside
Room was dirty and AC was broken. They gave us a new room after we spoke with them. Then we went to open the door to the new room and heard people talking as I grabbed the door handle, two men walked out. I complained to the manager and he started arguing with me. This place has really gone down ...
Reviewed on 12 Mar 2026
Discover top hotels, vacation package, cheap car rental deals and more with Wotif!
More Destinations
- Air Canada Tokyo (HND) to San Diego (SAN) flights
- Alaska Airlines New York (JFK) to San Diego (SAN) flights
- American Airlines Burlington (BTV) to San Diego (SAN) flights
- American Airlines Daytona Beach (DAB) to San Diego (SAN) flights
- American Airlines Cedar Rapids (CID) to San Diego (SAN) flights
- American Airlines Copenhagen (CPH) to San Diego (SAN) flights
- British Airways Warsaw (WAW) to San Diego (SAN) flights
- China Airlines Kaohsiung (KHH) to San Diego (SAN) flights
- China Eastern Airlines Dallas (DFW) to San Diego (SAN) flights
- China Eastern Airlines San Francisco (SFO) to San Diego (SAN) flights
- Delta Brainerd (BRD) to San Diego (SAN) flights
- Delta Genoa (GOA) to San Diego (SAN) flights
- Delta Omaha (OMA) to San Diego (SAN) flights
- Delta Greenville (GSP) to San Diego (SAN) flights
- Delta Myrtle Beach (MYR) to San Diego (SAN) flights
- Delta Papeete (PPT) to San Diego (SAN) flights
- Finnair Frankfurt (FRA) to San Diego (SAN) flights
- Frontier Airlines Dallas (DFW) to San Diego (SAN) flights
- Frontier Airlines Milwaukee (MKE) to San Diego (SAN) flights
- Frontier Airlines Chicago (ORD) to San Diego (SAN) flights
- Hawaiian Airlines Kahului (OGG) to San Diego (SAN) flights
- Hawaiian Airlines Sydney (SYD) to San Diego (SAN) flights
- Japan Airlines Hong Kong (HKG) to San Diego (SAN) flights
- United Bozeman (BZN) to San Diego (SAN) flights
- United Erie (ERI) to San Diego (SAN) flights
- United Rio de Janeiro (GIG) to San Diego (SAN) flights
- United Idaho Falls (IDA) to San Diego (SAN) flights
- United Copenhagen (CPH) to San Diego (SAN) flights
- United Manchester (MHT) to San Diego (SAN) flights
- United Muskegon (MKG) to San Diego (SAN) flights
- Flights from Acapulco (ACA) to San Diego (SAN)
- Flights from Auckland (AKL) to San Diego (SAN)
- Flights from Albany (ALH) to San Diego (SAN)
- Flights from Barcelona (BCN) to San Diego (SAN)
- Flights from Bilbao (BIO) to San Diego (SAN)
- Flights from Blackall (BKQ) to San Diego (SAN)
- Flights from Broome (BME) to San Diego (SAN)
- Flights from Canberra (CBR) to San Diego (SAN)
- Flights from Christchurch (CHC) to San Diego (SAN)
- Flights from Cleveland (CLE) to San Diego (SAN)
- Flights from Carlsbad (CNM) to San Diego (SAN)
- Flights from Catania (CTA) to San Diego (SAN)
- Flights from Cincinnati (CVG) to San Diego (SAN)
- Flights from Mudgee (DGE) to San Diego (SAN)
- Flights from Durango (DRO) to San Diego (SAN)
- Flights from Darwin (DRW) to San Diego (SAN)
- Flights from Des Moines (DSM) to San Diego (SAN)
- Flights from Erie (ERI) to San Diego (SAN)
- Flights from Eugene (EUG) to San Diego (SAN)
- Flights from Fort Lauderdale (FLL) to San Diego (SAN)
- Flights from Spokane (GEG) to San Diego (SAN)
- Flights from Glasgow (GLA) to San Diego (SAN)
- Flights from Gladstone (GLT) to San Diego (SAN)
- Flights from Hobart (HBA) to San Diego (SAN)
- Flights from Huntsville (HSV) to San Diego (SAN)
- Flights from Hamilton Island (HTI) to San Diego (SAN)
- Flights from Idaho Falls (IDA) to San Diego (SAN)
- Flights from Indianapolis (IND) to San Diego (SAN)
- Flights from Kalbarri (KAX) to San Diego (SAN)
- Flights from King Island (KNS) to San Diego (SAN)
- Flights from Kununurra (KNX) to San Diego (SAN)
- Flights from Leeds (LBA) to San Diego (SAN)
- Flights from Learmonth (LEA) to San Diego (SAN)
- Flights from Longreach (LRE) to San Diego (SAN)
- Flights from Lyon (LYS) to San Diego (SAN)
- Flights from Mexico City (MEX) to San Diego (SAN)
- Flights from Mount Gambier (MGB) to San Diego (SAN)
- Flights from Merimbula (MIM) to San Diego (SAN)
- Flights from Monterey (MRY) to San Diego (SAN)
- Flights from Tokyo (NRT) to San Diego (SAN)
- Flights from Oklahoma City (OKC) to San Diego (SAN)
- Flights from Ontario (ONT) to San Diego (SAN)
- Flights from Cooma (OOM) to San Diego (SAN)
- Flights from Norfolk (ORF) to San Diego (SAN)
- Flights from Perth (PER) to San Diego (SAN)
- Flights from Philadelphia (PHL) to San Diego (SAN)
- Flights from Pittsburgh (PIT) to San Diego (SAN)
- Flights from Proserpine (PPP) to San Diego (SAN)
- Flights from Papeete (PPT) to San Diego (SAN)
- Flights from Prague (PRG) to San Diego (SAN)
- Flights from Puerto Vallarta (PVR) to San Diego (SAN)
- Flights from Rockhampton (ROK) to San Diego (SAN)
- Flights from Savannah (SAV) to San Diego (SAN)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from San Francisco (SFO) to San Diego (SAN)
- Flights from Springfield (SGF) to San Diego (SAN)
- Flights from Singapore (SIN) to San Diego (SAN)
- Flights from Salt Lake City (SLC) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (SAN)
- Flights from Sydney (SYD) to San Diego (SAN)
- Flights from Weipa (WEI) to San Diego (SAN)
- Flights from Wagga Wagga (WGA) to San Diego (SAN)
- Flights from Wellington (WLG) to San Diego (SAN)
- Flights from Airlie Beach (WSY) to San Diego (SAN)
- Flights from Edmonton (YEG) to San Diego (SAN)
- Flights from Ottawa (YOW) to San Diego (SAN)
- Flights from Regina (YQR) to San Diego (SAN)
- Flights from Vancouver (YVR) to San Diego (SAN)
- Flights from Calgary (YYC) to San Diego (SAN)
- Flights from Zürich (ZRH) to San Diego (SAN)
^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.