American Airlines Flights from Fort Myers (RSW) to Greenville (GSP)

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Cheapest American Airlines Flights from Fort Myers (RSW) to Greenville (GSP)

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines Flights from RSW to GSP

How much is a American Airlines flight from Fort Myers (RSW) to Greenville (GSP)?

One-way flights start as little as NZ$454 and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.

How many non-stop American Airlines flights from Fort Myers (RSW) to Greenville (GSP) are there per day?

American Airlines flies flights direct every day between Fort Myers (RSW) and Greenville (GSP).

How far is Fort Myers (RSW) from Greenville (GSP)?

It’s from Fort Myers (RSW) to Greenville (GSP).

What is the best airline to fly from Southwest Florida Intl.?

At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Southwest Florida Intl. with: American Airlines. 

Can I change or cancel my American Airlines tickets from Fort Myers to Greenville on Wotif?

Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.

How do I find the best deal on American Airlines flights from Fort Myers (RSW) to Greenville (GSP)?

Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Fort Myers. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!

What’s a good way to get cheap American Airlines flight tickets from Fort Myers to Greenville?

We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!

What is the cheapest time of year to fly from Fort Myers (RSW) to Greenville (GSP)?

The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is March. Check our deal cards for details.

How long does it take to fly from RSW to GSP?

It typically takes hours to fly directly from Fort Myers (RSW) to Greenville (GSP).

Epic Hotel in Greenville

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
Great property.

Reviewed on 11 Mar 2026

Hampton Inn & Suites Greenville Airport, SC
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
Air condition was good. Shuttle left on time.

Reviewed on 6 Mar 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
The staff was ABSOLUTELY, ABSOLUTELY AMAZING!!! They were very courteous and helpful when we first walked through the main entrance and throughout our stay!!! Will definitely stay at this location again!!💕💕

Reviewed on 3 Mar 2026

Greenville Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.