Flights from St. Louis (STL) to San Diego (SAN)

Choose two or more items and save on your trip:

Change your flight without a fee on select flights

Money Saving Bundle when you purchase Hotel + Flight! 

Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app


St. Louis to San Diego Flight Information

Find the Cheapest Flights from St. Louis (STL) to San Diego (SAN)

Work hard, travel harder! Wotif brings you the cheapest St. Louis to San Diego flights, making it possible to have a five star holiday without that five star price tag. Browse and compare our top STL to SAN routes and airport options. So, go ahead and treat yourself, your sweetheart, or the kids to an unforgettable holiday this year.

to Information

Traveling From
Lambert-St. Louis Intl.
Origin Airport
Origin Airport IATA Code
STL
Traveling To
San Diego Intl.
Destination Airport
Destination Airport IATA Code
SAN
Number of Airlines Serving
Average Flight Time
hours mins
Direct Flight Time
hours mins
Flight Price
Address:
Airport Drive
San Diego CA, 92101
United States
IATA code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time zone:
America/Los_Angeles
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time zone:
America/Chicago

St. Louis to San Diego Flight Deals from

Considering a quick trip to San Diego, but not sure which is the best route for you? Well, you’re in luck! Wotif has done the hard work, so all you need to do is check out these flights from STL to SAN. With heaps of cheap fares from St. Louis, we guarantee you’ll be arriving to your holiday destination in style without emptying your bank account in the process.

It’s easy to book flights to San Diego from St. Louis  

For a huge choice of flights, simply enter your travel dates and hit search and we’ll hunt out fantastic deals on one-way, return and multi-city airfares to San Diego from St. Louis from different airlines. If you click the ‘direct flights’ box, you see flights that’ll get you to San Diego in just hour(s) and mins, too.   

Snap up great deals on flights to San Diego from St. Louis 

Choose from flights a day on average, with prices starting at and rising to depending on the cabin class, travel dates, and airline carrier. And if you’re up for a last-minute getaway, you can get great deals on flights from St. Louis to San Diego today!  

Find cheap airfares to San Diego from St. Louis 

Here are our insider tips for bagging a flight bargain: 

  • Look for midweek flights and late night, early morning arrival and departure times
  • Check out other airports near St. Louis and San Diego
  • Avoid peak season (prices tend to be lower in )
  • Be flexible with your travel dates and you can usually get cheaper options  

Reasons to book your flights to San Diego from St. Louis with Wotif

Wotif is a super-easy way to find the best flight for you to San Diego. Get more bang for your buck on flight and hotel or car rental combos and download the free Wotif app to tap into exclusive deals. Book now with Wotif and have a great flight!

 

Great places to stay after flight from St. Louis to San Diego

Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is NZ$398 per night from 26 May to 27 May
NZ$398
includes taxes & fees
26 May - 27 May
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,611 reviews)
"Close to airport"

Reviewed on 29 Apr. 2025

Sheraton San Diego Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is NZ$297 per night from 11 May to 12 May
NZ$297
includes taxes & fees
11 May - 12 May
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,692 reviews)
"good"

Reviewed on 3 May 2025

Wyndham San Diego Bayside
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is NZ$269 per night from 6 May to 7 May
NZ$269
includes taxes & fees
6 May - 7 May
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,556 reviews)
"Great"

Reviewed on 29 Apr. 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.