American Airlines Flights from Charlotte (CLT) to Key West (EYW)
Change your flight without a fee on select flights
Money Saving Bundle when you purchase Hotel + Flight!
Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app
American Airlines Flights from CLT to EYW
How much is a American Airlines flight from Charlotte (CLT) to Key West (EYW)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Charlotte (CLT) to Key West (EYW) are there per day?
American Airlines flies flights direct every day between Charlotte (CLT) and Key West (EYW).
How far is Charlotte (CLT) from Key West (EYW)?
It’s from Charlotte (CLT) to Key West (EYW).
What is the best airline to fly from Charlotte-Douglas Intl.?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Charlotte-Douglas Intl. with: .
Can I change or cancel my American Airlines tickets from Charlotte to Key West on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Charlotte (CLT) to Key West (EYW)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Charlotte. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Charlotte to Key West?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Charlotte (CLT) to Key West (EYW)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from CLT to EYW?
It typically takes hours to fly directly from Charlotte (CLT) to Key West (EYW).
Epic Hotel in Key West
Hyatt Vacation Club at Windward Pointe, Key West
Amazing place and we will consider this again!
Reviewed on 18 Mar 2026
Hampton Inn Key West FL
Spacious rooms with friendly staff. Most staff don’t speak English well but are friendly. Property is well kept. Paid parking through an app was kind of spendy. Pool was nice but needs more lounge chairs. Airport is very close and can be quite loud but flights stop fairly early. Not close to downtown ...
Reviewed on 18 Mar 2026
DoubleTree Resort by Hilton Grand Key - Key West
Enjoyed myself here, the pool and hot tub were great. The onsite restaurant was delicious. Our room was clean and odor free. It was a great pick for our stay!
Reviewed on 17 Mar 2026
Discover top hotels, vacation package, cheap car rental deals and more with Wotif!
More Destinations
- Alaska Airlines San Francisco (SFO) to Key West (EYW) flights
- American Airlines Charlottesville (CHO) to Key West (EYW) flights
- American Airlines Rochester (ROC) to Key West (EYW) flights
- American Airlines Roswell (ROW) to Key West (EYW) flights
- American Airlines Boston (BOS) to Key West (EYW) flights
- American Airlines Midland (MAF) to Key West (EYW) flights
- American Airlines Salt Lake City (SLC) to Key West (EYW) flights
- American Airlines Savannah (SAV) to Key West (EYW) flights
- British Airways London (LHR) to Key West (EYW) flights
- Delta Albuquerque (ABQ) to Key West (EYW) flights
- Delta Charleston (CHS) to Key West (EYW) flights
- Delta Columbia (CAE) to Key West (EYW) flights
- Delta Columbus (CSG) to Key West (EYW) flights
- Delta Jackson (JAN) to Key West (EYW) flights
- Delta Columbus (GTR) to Key West (EYW) flights
- Delta Lincoln (LNK) to Key West (EYW) flights
- Delta Newark Liberty Intl. Airport (EWR) to Key West (EYW) flights
- Delta San Diego (SAN) to Key West (EYW) flights
- Delta Houston (HOU) to Key West (EYW) flights
- Jetblue Airways Detroit (DTW) to Key West (EYW) flights
- Jetblue Airways Nassau (NAS) to Key West (EYW) flights
- Jetblue Airways Aguadilla (BQN) to Key West (EYW) flights
- Klm Frankfurt (FRA) to Key West (EYW) flights
- United Green Bay (GRB) to Key West (EYW) flights
- United Bozeman (BZN) to Key West (EYW) flights
- United Allentown (ABE) to Key West (EYW) flights
- United Billings (BIL) to Key West (EYW) flights
- United Manchester (MHT) to Key West (EYW) flights
- United Newark Liberty Intl. Airport (EWR) to Key West (EYW) flights
- United Champaign (CMI) to Key West (EYW) flights
- Flights from Albury (ABX) to Key West (EYW)
- Flights from Adelaide (ADL) to Key West (EYW)
- Flights from Auckland (AKL) to Key West (EYW)
- Flights from Albany (ALB) to Key West (EYW)
- Flights from Atlanta (ATL) to Key West (EYW)
- Flights from Wilkes-Barre (AVP) to Key West (EYW)
- Flights from Ayers Rock (AYQ) to Key West (EYW)
- Flights from Bundaberg (BDB) to Key West (EYW)
- Flights from Bangor (BGR) to Key West (EYW)
- Flights from Broken Hill (BHQ) to Key West (EYW)
- Flights from Bathurst (BHS) to Key West (EYW)
- Flights from Blackwater (BLT) to Key West (EYW)
- Flights from Nashville (BNA) to Key West (EYW)
- Flights from Ballina (BNK) to Key West (EYW)
- Flights from Bourke (BRK) to Key West (EYW)
- Flights from Burnie (BWT) to Key West (EYW)
- Flights from Canberra (CBR) to Key West (EYW)
- Flights from Cairns (CNS) to Key West (EYW)
- Flights from Carnarvon (CVQ) to Key West (EYW)
- Flights from Washington (DCA) to Key West (EYW)
- Flights from Dallas (DFW) to Key West (EYW)
- Flights from Devonport (DPO) to Key West (EYW)
- Flights from Esperance (EPR) to Key West (EYW)
- Flights from Newark Liberty Intl. Airport (EWR) to Key West (EYW)
- Flights from Fort Lauderdale (FLL) to Key West (EYW)
- Flights from Frankfurt (FRA) to Key West (EYW)
- Flights from Griffith (GFF) to Key West (EYW)
- Flights from Gainesville (GNV) to Key West (EYW)
- Flights from Greenville (GSP) to Key West (EYW)
- Flights from Hobart (HBA) to Key West (EYW)
- Flights from Hamilton Island (HTI) to Key West (EYW)
- Flights from Hervey Bay (HVB) to Key West (EYW)
- Flights from Houston (IAH) to Key West (EYW)
- Flights from Mount Isa (ISA) to Key West (EYW)
- Flights from Jacksonville (JAX) to Key West (EYW)
- Flights from Kangaroo Island (KGC) to Key West (EYW)
- Flights from Kununurra (KNX) to Key West (EYW)
- Flights from Karratha (KTA) to Key West (EYW)
- Flights from Lord Howe Island (LDH) to Key West (EYW)
- Flights from Launceston (LST) to Key West (EYW)
- Flights from Kansas City (MCI) to Key West (EYW)
- Flights from Orlando (MCO) to Key West (EYW)
- Flights from Harrisburg (MDT) to Key West (EYW)
- Flights from Melbourne (MEL) to Key West (EYW)
- Flights from Monkey Mia (MJK) to Key West (EYW)
- Flights from Mackay (MKY) to Key West (EYW)
- Flights from Maningrida (MNG) to Key West (EYW)
- Flights from Mildura (MQL) to Key West (EYW)
- Flights from Moree (MRZ) to Key West (EYW)
- Flights from Moruya (MYA) to Key West (EYW)
- Flights from Narrabri (NAA) to Key West (EYW)
- Flights from Olympic Dam (OLP) to Key West (EYW)
- Flights from Philadelphia (PHL) to Key West (EYW)
- Flights from Port Lincoln (PLO) to Key West (EYW)
- Flights from Port Macquarie (PQQ) to Key West (EYW)
- Flights from Roma (RMA) to Key West (EYW)
- Flights from St. Louis (STL) to Key West (EYW)
- Flights from Sydney (SYD) to Key West (EYW)
- Flights from Tampa (TPA) to Key West (EYW)
- Flights from Taree (TRO) to Key West (EYW)
- Flights from Wagga Wagga (WGA) to Key West (EYW)
- Flights from Toowoomba (WTB) to Key West (EYW)
- Flights from Fayetteville (XNA) to Key West (EYW)
- Flights from Newman (ZNE) to Key West (EYW)
^Savings based on all package bookings made with Flight + Hotel on Wotif.co.nz from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.